hepatitis b infection during renal replacement therapy

Hepatitis B Infection during Renal Replacement Therapy

H B virus (HBV) infection in patients with end-stage renal disease (ESRD) on renal replacement therapy—hemodialysis and/or renal transplantation—usually has an unfavorable course with a tendency towards chronicity leading to increased morbidity and mortality (1). Furthermore, the patients with the infection remain a source of nosocomial infection during hemodialysis. Though the incidence of HBV...

Hepatitis C virus infection in patients on renal replacement therapy

Hepatitis C virus infection is a frequent clinical problem in patients on dialysis and renal transplant recipients. The local prevalence rates of hepatitis C virus infection in patients on peritoneal dialysis, hemodialysis, or after kidney transplantation are 2%, 9%, and 6%, respectively. Conventional diagnosis of hepatitis C virus infection is by anti-hepatitis C virus immunoassays. However, u...

‘Biomarking’ infection during continuous renal replacement therapy: still relevant?

We greatly appreciated the recent research article by Park and colleagues in Critical Care showing that procalcitonin (PCT) is not superior to C-reactive protein (CRP) as a marker for infection in renal impairment [1]. Additionally, we would like to comment on the validity of CRP and PCT measurement during continuous renal replacement therapy (CRRT). Both acute-phase proteins are indeed effecti...

Hepatitis B infection: review article

Hepatitis B virus (HBV) is an etiological agent of hepatitis B infection. Hepatitis B is a life-threatening disease that affects the liver. The clinical outcomes of the disease are varied from asymptomatic disease to serious complication such as cirrhosis and hepatocellular carcinoma (HCC). Despite availability of the vaccine and appropriate treatment, hepatitis B infection still remains a majo...

Hepatitis B Infection in End-Stage Renal Disease Patients in Khuzestan Province, Iran

Drug dosing during continuous renal replacement therapy.

Continuous renal replacement therapy (CRRT) has given clinicians an important option in the care of critically ill patients. The slow and continuous dialysate and ultrafiltrate flow rates that are employed with CRRT can yield drug clearances similar to an analogous glomerular filtration rate of the native kidneys. Advantages such as superior volume control, excellent metabolic control, and hemo...